November 2015 - Biowebspin | Biowebspin
Logo Biowebspin

Archives November 2015 - Biowebspin

Zebrafish_embryos-blog

Industry–academia collaborations for biomarkers

  Biowebspin, November 27th, 2015 Industry–academia collaborations for biomarkers by Khusru Asadullah, Andreas Busch, Matthias Gottwald, Petra Reinke & Lilla Landeck, in NATURE REVIEWS DRUG DISCOVERY, 2015 Several types of collaboration are being pursued to identify, validate and apply new biomarkers. Here, we highlight examples of such initiatives and discuss the challenges, approaches to add... »

Chest-Xray-Blog

Open Innovation in Health Care

  Biowebspin, November 25th, 2015 Open Innovation in Health Care by Ronny Reinhardt, Angelika C. Bullinger, Sebastian Gurtner, in Challenges and Opportunities in Health Care Management, 2015 Traditionally, the dominant form of innovation required that firms generate ideas internally and subsequently develop and market resulting products themselves. Yet, this mode of innovation is not always the be... »

Blog-Binocular

Open innovation and intellectual property: time for a reboot?

  Biowebspin, November 23rd, 2015 Open innovation and intellectual property: time for a reboot? by Duncan B. Judd in Drug Discovery Today, 2013   Get Full text:  »

A crowd-sourcing approach for the construction of species-specific cell signaling networks

A crowd-sourcing approach for the construction of species-specific cell signaling networks

  Biowebspin, November 18th, 2015 A crowd-sourcing approach for the construction of species-specific cell signaling networks by Erhan Bilal, Theodore Sakellaropoulos, Challenge Participants,Ioannis N. Melas, Dimitris E. Messinis, Vincenzo Belcastro, Kahn Rhrissorrakrai, Pablo Meyer, Raquel Norel, Anita Iskandar, Elise Blaese, John J. Rice, Manuel C. Peitsch, Julia Hoeng, Gustavo Stolovitzky, Leoni... »

chemical-blog

A Crowdsourcing Evaluation of the NIH Chemical Probes

Biowebspin, November 17th, 2015 A Crowdsourcing Evaluation of the NIH Chemical Probes by Tudor I. Oprea, Cristian G. Bologa, Scott Boyer, Ramona F. Curpan, Robert C. Glen, Andrew L. Hopkins, Christopher A. Lipinski, Garland R. Marshall, Yvonne C. Martin, Liliana Ostopovici-Halip, Gilbert Rishton, Oleg Ursu, Roy J. Vaz, Chris Waller, Herbert Waldmann, and Larry A. Sklar in Nat Chem Biol., 2009 Betw... »

Chest-Xray-Blog

Fueling Open-Source Drug Discovery: 177 Small-Molecule Leads against Tuberculosis

  Biowebspin, November 16th, 2015 Fueling Open-Source Drug Discovery: 177 Small-Molecule Leads against Tuberculosis by Lluís Ballell, Robert H Bates, Rob J Young, Daniel Alvarez-Gomez, Emilio Alvarez-Ruiz, Vanessa Barroso, Delia Blanco, Benigno Crespo, Jaime Escribano, Rubén González, Sonia Lozano, Sophie Huss, Angel Santos-Villarejo, José Julio Martín-Plaza, Alfonso Mendoza, María José Rebollo-Lo... »

Oncology drug development – Activating the 5R factors

Oncology drug development – Activating the 5R factors

  Biowebspin, November 13th, 2015 Oncology drug development - Activating the 5R factors by Susan Galbraith in Cancer Control, 2015 Over 1.8 million people were diagnosed with lung cancer in 2012, making it the most common form of cancer worldwide. It is the leading cause of cancer deaths in men, the second in women and 1.59 million people die annually from the disease. Although there have been sig... »

Blog-Surgery

Key drivers of biomedical innovation in cancer drug discovery

  Biowebspin, November 11th, 2015 Key drivers of biomedical innovation in cancer drug discovery by Margit A Huber and Norbert Kraut in EMBO molecular medicine, 2015 Discovery and translational research has led to the identification of a series of “cancer drivers”—genes that, when mutated or otherwise misregulated, can drive malignancy. An increasing number of drugs that directly target such driver... »

Opening the door to innovation

Opening the door to innovation

  Biowebspin, November XXth, 2015 Opening the door to innovation by Janine Schuurman, Yvo F Graus, Aran F Labrijn, Sigrid R Ruuls, and Paul WHI Parren in Landes Bioscience, 2015 Open innovation is the new buzz, with initiatives popping up left and right. Here, we give a personal perspective on a very successful, knowledge-driven innovation initiated in an academia- industry alliance, which culmina... »

Blog-Mice

Making Progress and Gaining Momentum in Global 3Rs Efforts: How the European Pharmaceutical Industry Is Contributing

  Biowebspin, November 5th, 2015 Making Progress and Gaining Momentum in Global 3Rs Efforts: How the European Pharmaceutical Industry Is Contributing by Gill Fleetwood, Magda Chlebus, Joachim Coenen, Nicolas Dudoignon, Catherine Lecerf, Catherine Maisonneuve, and Sally Robinson in Journal of the American Association for Laboratory Animal Science, 2015 Animal research together with other investigat... »