New solutions to replace solvents for solid phase peptide synthesis - Biowebspin | Biowebspin
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External open innovation partner programNew solutions to replace solvents for solid phase peptide synthesis
Are you working on peptide synthesis? Are you interested in partnering with a top 5 pharma company to translate your new science into a new medicine?
What we are looking for

The replacement of both DMF (dimethylformamide) and NMP (N-methylpyrrolidone) as polar, aprotic solvents - currently "the solvents of choice" for solid phase peptide synthesis - by eco-friendly solvents is targeted both by the EU chemical legislation and our company. Since a while we are exploring alternative solvents, aimed to demonstrate comparable efficiency in solid phase peptide synthesis as obtained with DMF or NMP in terms of yield, product purity, throughput, key starting material & intermediate solubility, resin swelling properties and so on.

As of this, we are looking for new solutions to avoid the use of DMF and NMP as polar, aprotic solvents in peptide synthesis processes.
Especially we would be interested to find out whether solvents with similar chemical and physical properties would be readily available e.g. from plants or other sources or if there were already new established peptide synthesis processes avoiding the use of DMF and NMP.

What we offer and how does it work

All proposals will be assessed by our Research & Development team. Based on the level of interest within the Company research portfolio and strategic fit, we will enter into discussion with selected candidate(s), potentially leading to partnership agreements or collaborations.

Proponents that submit proposals of interest will be contacted to clarify additional details.

What to submit

Submit a proposal in a form which is available online (it takes about 15 minutes). The proposal should be brief, sufficient to provide the main body of the proposal and its innovativeness. The applicant should also provide information about his or her critical knowledge that is applicable for the project, and how the knowledge could be supplemented (i.e., what is additionally required to complete the project). The applicants are strongly encouraged to give us additional information including references or other materials to facilitate the evaluation process.

Privacy, confidentiality & FAQ

The Company will not share the information beyond its own staff and its Consultants; your initial proposal should contain only non-confidential information.
If your proposal is selected, the Company is open to complete a Confidentiality Disclosure Agreement (CDA).


Biowebspin pays a lot of attention to the privacy, intellectual property, confidentiality and security of its member data.</p> <p>Biowebspin is a matchmaking platform between academia & industry. Biowebspin is not involved in the IP discussion and is not charging any success or license fees. Your «Open Innovation» opportunities on Biowebspin are only visible by industrials and the Biowebspin team. You can remove your data at any time. Biowebspin strongly recommends that you do not enter any confidential data or if you do so, that your technology transfer office agrees the submission of your pre-proposal on Biowebspin. If you directly submit your pre-proposal on an industrial partner website, you will agree their terms, conditions and privacy policy of our industrial partner website. Biowebspin is not responsible for the content, accuracy, or opinion of its industrial partner website. As a Swiss International company, Biowebspin has high standard security and privacy system. Biowebspin is in accordance with the Federal Data Protection and Information Commissioner. Contact us for more information about the terms and conditions of the matchmaking service of Biowebspin.